OK. It has been ages since I posted last. I just saw this article and though it was a good place to start. In the fungal pathogen world, there is a lot of debate about "what makes a pathogen" - basically, many of the human fungal pathogens out there are considered "opportunists" in that in a normal human host they are not able to cause disease. Well at least rarely are they a problem in healthy people. MFF (my fav fungus) Coccidioides is a bit more of a bear in that respect- it really does infect and kill healthy people. But a bit of an outlier.
This article reviews what is known about genomic differences between a bread mold and a pathogen. Really, there is not that much difference (and never mind that occasionally the bread mold WILL cause disease) but there are some trends that pop out. The ability to: stick to surfaces, be resistant to anti-fungal drugs, and basically be flexible- in your food source, your genetic make up and your morphology.
Another nice aspect is that the article is open source! Devour at will!
Hormone replacement therapy is beneficial and safe, it turns out
-
A new study that just appeared in the Journal of the American Medical
Association has some good news for women who take estrogen replacement
therapy.
...
1 week ago
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